A young woman returns to the secluded, abandoned psychological research facility where her deceased mother once worked. Accompanied by three friends, she discovers that the ghosts of the past have found their way to the present when the hospital's legacy of experimentation and madness tears away all known bounds of time, memory and space.

Hostage in his own home, an incompetent Englishman is forced to team up with his captor to fight off the survivors of a fatal flu epidemic.